Artemisinin is sesquiterpene lactone of peroxide groups extracted from artemisia aunna
Common Name: Artemisinin
Molecular Formula: C15H22O5
Molecular Weight: 282.33
Properties: Colorless needle crystal with bitter taste
Content (HPLC): 97.0% - 102.0%
Chinese antimalarial drug research was originated the 523 Project established in 1967, or the Chinese Malaria Research Collaboration Project, which was founded on May 23, 1967. Because it was then a top-secret military project, the Project was code-named 523.
After 380 times of murine malaria screening, the herbal medicine artemisinin was successfully separated in October 1971. In 1972, the effective antimalarial monomer was isolated from the herbal medicine artemisia annua and was named artemisinin, with which the parasites of murine malaria and simian malaria could be inhibited 100%.
In 1973, clinical findings ran consistent with laboratory results, and the antimalarial drug artemisinin was born.
In October 1981, the presentation "A Chemical Research on Artemisinin" made by the Chinese representative on the International Artemisinin Conference in Beijing organized by the World Health Organization raised great interest among the participants, who agreed that the more important significance of these new discovery was that it pointed out the direction for the further design and synthesis of new drugs.
In 1986, artemisinin was awarded the certificate of new drugs, and so was dihydroartemisinin. These results received the National Invention Award and the National Top Ten Technology Achievement Award.
In September 2011, the Chinese female pharmacists, Tu Yoyo, invented the new antimalarial drug, artemisinin and dihydroartemisinin, and was given the Lasker Award, known as the "wind vane" of the Nobel Prize. This is the most prestigious world-class award ever received by the China's biomedical community.
In October 2015, Tu Youyou won the Nobel Prize in Physiology and Medicine. She was the first native Chinese scientist to win the Nobel Prize in Science. The first Chinese scientist to win the Nobel Prize in Physiology and Medicine.
World Health Organization Recommendations
World Health Organization, after summarizing and analyzing the anti-malaria work around the world, believes that the use of single artemisinin is likely to cause resistance of malaria parasites, and proposes to opt for artemisinin-based combination therapy (ACT) instead of single artemisinin.